Motor neurone disease: the nature of the pathogenic mechanism

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The management of motor neurone disease.

Correspondence to: Professor P N Leigh, King’s MND Care and Research Centre, Department of Neurology, Institute of Psychiatry and Guy’s King’s and St Thomas’s School of Medicine, PO Box 41, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK; [email protected] _________________________ T he management of motor neurone disease (MND) has evolved rapidly over the last two decades. Althou...

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Motor neurone disease.

Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features are manifest. For all forms of the disease there is a significant differential d...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1974

ISSN: 0022-3050

DOI: 10.1136/jnnp.37.9.1036